Study and offer the strong means for studying on the body in molecule image
Author: Pan Feng
It is a new developing cross discipline that the molecule image is studied, involve a plurality of disciplines such as information science, molecular biology, chemistry, physics, clinical medicine and pharmacy. Israel that was holding a few days ago " The key science and technology of the molecule image and employing " It is at the 338th Fragrant Hills international symposium of scientific meeting of the theme, the expert participating in the conference points out, the research focus of fields of crossing that the molecule image has already become multi-disciplinary, a large number of basic sciences problems to be solved not merely exist, and is facing the new break-through on the application.
It is in the body, real-time, trends that the molecule image technology can realize biological organism physiology, pathology to change at the molecule level, have three-dimensional formation of image created, in order to study the particular genetic function, the organism grows, disease is developed and is applied result appraising and medicine supersession dynamics,etc. and offered information acquisition and means effectively to analyse and process with the medicine.
Chinese Academy of Sciences the intersection of living beings and physical Wei Liang, researcher of research institute, point out isolate the dispersible result of study, combine outside the body people in the past, attempt to rebuild the course of the life, this kind of research way has deviated from systematicness and complexity of the organism greatly, make people's understanding of biological phenomena offset, but the present research means can't meet behavioral research to the single molecule in the life entity on space and time far. The molecule image learns the research in order to be realized at the body molecule level, in order to announce emergence and research and development of development, medicine and appraisal of activity law of the life, disease,etc. have offered the strong means.
Professor of Peking University first hospital Wang FuRong introduces for example, molecule nuclear medicine is that the technology of molecular biology and modern radioactive nuclide show a new branched discipline of nuclear medicine that track technology combines together and produces. Utilize radioactive nuclide to show track technology and know disease from molecule level, expound such mechanisms as the blood flow, supersession, receptor density and change, unusual expression, biochemical supersession of gene of the function of the target organ or tissue change and conduct with cell information, have offered the relevant information at the molecule level for diagnosis in early days, treating with the basic research effectively of disease, it is the front of medical research of our times. Executive chairman, Tsing-Hua University Professor of the meeting are fair and clear introduces optical member's image research and current application situations and development trends, point out fluorogenic member succeeds it is like a kind of new technology of formation of image of molecule, it utilizes to organize the fluorogenic probe with affinity to follow the biological course to the particular goal on the body, respect of controlling etc. has great using value to measure, new medicine researching and developing, drug effect at tumour.
Executive chairman of the meeting, automatic researcher of research institute Tian Jie of Chinese Academy of Sciences has summarized the theory innovation achievement already made in the field of molecule image in recent years, break-through and preliminary application of several key technology are popularized etc., emphasize it is in fast development state that the molecule image learns to study straightly. While looking like the mode, no form modes are perfect at present that Tian Jie thinks, in various molecules are apparent, many modes merge and already become the systematic development trend of the biomedical formation of image, sound, light, heat, magnetism, synthesis of technology such as being nuclear integrate, employ, study, open up wide research and application space for the intersection of member and formation of image. Tian Jie explains, the formation of image of spontaneous fluorogenic fault (BLT) , bring out fluorogenic the intersection of fault and formation of image (FMT) , the optical formation of image (DOT) of disperse , many kinds of modal integration such as CT, can offer at the same time swifter and analyzing degree, high structure that distinguishes and function formation of image accurately, high, improve the quality of the formation of image, and will promote the scientific and technological progress of the biological medicine field greatly.
The expert participating in the conference thinks, it becomes with optics it is two kinds of main molecule images that study the technological method that the nuclide forms images, the method of these two kinds of formations of image each has pluses and minuses, the more important thing is what a question in coordination with development it is. The expert proposes, strengthen the integration alternately in the technical research of formation of image of molecule, including the hardware, the integration of the software, develop the detector of the new and simple and easy molecule image; Through the support to industry of the state policies, let more researchers and clinicians use the molecule image apparatus of the independent intellectual property right; In medicine research, study and guide the standardization that researches and develops of Chinese medicine with the molecule image; On cognitive science, start the research of launching the cognitive member's image.
Study and offer the strong means for studying on the body in molecule image
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