Utilize gene therapy to lose one's sight and succeed

Utilize gene therapy to lose one's sight and succeed Promote gene therapy well
American researchers say, 1 year ago, 3 blind volunteers about 20 years old accepted gene therapy, now, these volunteers' eyesight gets the improvement of a certain degree, a volunteer can read the figure on the car gauge board, relevant research is issued on " medical magazine of New England " published on the 12th.

These 3 volunteers all suffer from favorable uncle's inborn black cataract - -The retinal eye illness of a kind of heredity, because one kind is RPE65 (RPE65 gene produces a kind of special vitamin A for retinal cells) Gene eyesight lasted patiented to appear fail with growth of age, some people will lose one's sight after growing up, there is no effective treatment yet at present to this kind of disease.

The group of swallow of Sri Lankan Germany Sri Lankan of picture of A of University of Pennsylvania injects DNA with normal function into the virus, and then inject virus into the patient's eye cells. 3 months later, the eyesight of 3 patients receiving treatment is improved to some extent, can catch the light with the naked eye, they are unable to accomplish at all before this. Moreover, after treating for one year, any immunoreaction did not appear in the patient's eye and body.

Among them a woman patient has produced in the course of treating " Second eyesight " ,Visit and fetch information in a certain retinal area where her brain has already learnt to rejuvenate again since accept gene therapy, make her read the figure on the gauge board.

In 1999, a teenager 18 years old who suffered from hepatopathy died 4 days after implementing gene therapy, causing gene therapy to be mauled, people hesitate to move forward to the gene therapy experiment especially.

The swallow claims, " very safe, moreover, the patient's eyesight has obviously steady improvement for RPE65 genetic treatment in Sri Lankan Germany Sri Lankan, hope to continue carrying on the test in order to solve key problems such as security and validity,etc. " .

In following a few years, researchers will observe the patient's state continuously, will do, test on other patients, in order to observe, it injects different DNA of quantity to be will be more effective.

The favourable uncle, inborn black cataract is one kind that the retinal pigment changed the sex, in U.S.A., about 2000 people suffer from favorable uncle's inborn black cataract; About 200,000 people suffer from the retinal pigment and change the sex. (Liu Xia)


Utilize gene therapy to lose one's sight and succeed Promote gene therapy well