Hedgehog's role in cancer of colon of thorough fare of

Hedgehog's role in cancer of colon of thorough fare of albumen signal is verified
It is reported one research group of Switzerland claim they find a may prevent the mankind from marry the new method that the colon-cancer cell grows and shifts August 27, and succeeded in animal's experiment. Relevant research issue at " Europe molecular biology learns the periodical " that publish the same day.

It is introduced, the morbidity position of the early cancer of colon mostly lie in the intestines wall, relatively easy treatment. But most cancer of colon has already arrived in the later period difficult to cure in the discovery in daily case. A research group in Geneva of Switzerland finds, while cancer of colon develops into later period, signal thorough fare of hedgehog's albumen (HH-GLI or Hedgehog-GLI) Have played an important role. HH-GLI is the signal thorough fare used for transmitting information between a kind of cell, generally used for confirming information such as cell surviving, development and position.

The professor of Palestine of riel Ruiz and Al tower says in Switzerland Geneva university responsible for this research, it is researched and proposed that relevant, HH-GLI assumption with important function in cancer of colon, but is denied by many scholars. This time, researchers have proved the important function of HH-GLI in surviving and development of cancer of colon through the experiment, and found in skin cells that has an active hedgehog albumen on cancer of colon. In addition, they also find shifting tumour will not keep growing unless depend on HH-GLI either. So, recognise HH-GLI and and regard it as the mark and offer a kind of new route for treatment of cancer of colon.

Particularly it is that the application RNA gets involved and the ring rake will be blocked tomorrow Hedgehog signal will conduct the thorough fare in the cancerous issue, in order to influence its subsequent gene expression, thus achieve the goal of preventing cancer cell from growing, shifting and recuring.

Researchers find, can also prevent the upgrading oneself of cancer cell by blocking HH-GLI by science of heredity or pharmacology means, this kind of treatment is effective too to the control that cancer shifts and recurs. In the experiment to the little mouse after the ring rake will be blocked and will treat tomorrow, tumour that originally exists in little mouse's body fades. It is still healthy to suffer from the little mouse of cancer after receiving treatment for one year, has not seen recuring or other uncomfortable symptoms.

Ruiz the intersection of Al and the intersection of tower and bar claim the research prove HH-GLI until mankind marry the important function in the the colon-cancer cell, open a new situation for the treatment of cancer, can can dispel tumour prevent its new method that recur and produce the side effect as well as after offering a. (Wang XiaoLong)

Hedgehog's role in cancer of colon of thorough fare of albumen signal is verified