Leukaemia cells of hour with recuring of first visit are different
It is reported ' Reporter Wang XueFei) According to latest Science report published on November 27, it is different from causing the cells of the initial leukemia to cause the cancer cells that acute leukemia recurs. Cancer cell and the comparative result of study of the leukaemia cell of the beginning when diagnose to the stage of recuring, may show the new target useful in treatment of cancer to recuring especially.
At present, over 80% of the children who suffer from the acute lymphocytic mother's cellulous leukemia can be cured, but it was very low that those went through the survival rate of the infant who recur after treating. CharlesMullighan and colleague that the holy fur coat morality child in U.S.A. studied the hospital have launched a research, suffer from acute lymphocytic the intersection of mother and cellulous the intersection of leukemia and two kinds of cell samples of children, copy, count, make a variation to analyze the whole genome DNA to 61. Found finally, " diagnosed " in cancer With " recur " In period, DNA of two kinds of cell samples copies and counts difference. They have also announced that copy and count unusual essence - -Gene that the abnormal state revealed mainly influenced the regulation and B cell with cell cycle to be relevant in development in the recurring. What especially merits attention is, nearly leukemia that half the cases recur takes the leukaemia cell of the subject when not stemming from diagnosis.
CharlesMullighan,etc. proposes, had a kind of beginning source leukaemia cell, produced cell and another different cells which start the initial leukemia (exist from it in diagnosis only with minority) . The latter has already gone through different science of heredity to change before appearing in the form of more fatal recurring cell. It may become the new target useful in treatment of cancer to recuring.
Leukaemia cells of hour with recuring of first visit are different
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