The endotoxin will cause chronic inflammation

The endotoxin will cause chronic inflammation
It is reported ' Reporter Hu DeRong) Life nutrition researcher of scientific research institute Lin Xu and group of research institute in Shanghai of Chinese Academy of Sciences find in the research of crowd of a larger scale for the first time, human the endotoxin ' Lipopolysaccharide) Conjugated proteln (LBP) There are prominent relations at level and chronic supersession disease and 2 type diabetes ill risk, the relevant research thesis was published in " diabetes was attended to " the magazine a few days ago.

A large amount of research shows, one of the important mechanisms that fat relevant supersession disease takes place that chronic inflammation is probably. However, it is not yet clear to causing risk factor and relevant mechanism of the chronic inflammation up until now. Animal's experiment reveals, the fatty food or endotoxin can stimulate the chronic inflammatory thorough fare, thus cause the supersession to be disorderly. The intestinal leather is blue the negative fungus is an endotoxic important source. LBP is one of the key members on the endotoxic thorough fare, can be regarded as the substituting index which reflects endotoxic level of the blood.

The this group one Sun Liang Dr.,etc. to overweight 559 persons /overweight person and 500 blood plasma LBP levels of weight normal measure, and do network analysis of the relation of its fat and relevant supersession disease, find: The overweight / fat individual's LBP level is higher than the normal weight individual notably; Blood plasma LBP level and physique index (BMI) , supersession indexes such as waistline, blood pressure, blood glucose, fat of blood, insulin,etc., and liver enzyme, inflammation factor are correlated with with the fat factor level notably; After controlling age, gender, smoking, drinking, physical exertion, disease family's history and BMI, the research object suffers from supersession syndrome, insulin and resists the danger with the 2 type diabetes to increase notably with rising of the blood plasma LBP level.



The endotoxin will cause chronic inflammation