It is " small " to clone And then there are a lot of things to be done
According to the report of Beijing (Xinhua) the 2nd August " on iPS cell, it is not enough to clone animals out yet with it, can the future generation who clones the animal be healthy? Where is the future generation again? All these need to continue studying. " Zhou Qi, researcher of Ins of animal,Academia Sinica, says in this way when being interviewed by reporter of Xinhua News Agency.
According to new British Nature, Ins of animal,Academia Sinica week fine jade and Beijing life sciences research institute high to continue research group that honour lead, utilize iPS cells respectively a few days ago ' Induce the multi-functional stem cell) Clone the mouse of experiment made on the living out, thus verify iPS cells are as all-round like embryo's stem cell. Among them, Zhou Qi's research group has succeeded in fostering 27 and testing mice, and clone first iPS cells the mouse names as " smallly " . This achievement is paid close attention to by the international stem cell's research circle, Nature websites praise a Chinese scientist " Have opened up a brand-new road in order to clone the adult mammal " .
"Clone out the little mouse, not meaning iPS cells, since this can be applied to medical treatment on a large scale, we have a lot of things to do. " Explain, it is the 1st generation of iPS cell technology that employ now, it needs to use virus as carriers to channel into the gene to foster it with week fine jade, so there are big risks. "We will advocate studying to channel into the gene for carriers with the small molecule or medicine albumen in the future, foster safer iPS cells. "
Zhou Qi thinks, it is " small " Birth and grow up healthy and sound only first,the it one reproduction quality OK, how is its health status of progeny, need further investigating. "In this research, we have cloned 27 and tested mice in the first batch, among them there is experimental mouse's death or an example that the health becomes abnormal too. "
But the fine jade shows, in the first batch of iPS cells clone mice, all 12 that are used for mating test mice and succeed in producing the offspring in week, and the second generation of these do not have abnormal phenomenon. They have born several hundred the second generation of experiment mice, and already had over 100 the third generation of experiment mice. The transcription factor that because uses in iPS cells could be totally expressed on the last several generations of experiments mouse, so the next work is the health status that further observes these offsprings, thus carry on more concrete appraisal of security to iPS cell technology.
It is " small " to clone And then there are a lot of things to be done
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