Veterinarian's administration may treat the river blind disease

Veterinarian's administration may treat the river blind disease
The beautiful and fragrant flowers it is reported researchers find, a can be used for treating filariasis of a record of end (also called the river blind disease) too by the medicine which the veterinarian used for killing ox's parasite ,The latter is a kind of parasitics infectious disease making the person weak, there is torment that 37 million people are suffering it in the whole world. But the expert warns, it is early to use this kind of medicine on people at present. According to American Science's online news, as people have been carried one kind and called tail filaria of plate (Onchocerca volvulus) Nematode black be infected with by records of tail filariasis after mosquito bite. With maturity and mating of larva of these nematodes, there will be more than 1000 sons worms that were born every day, the latter will migrate to top layer and eyes of the human skin. After death of worm of these young animals, the skin that they will result in making people itch is damaged, and cause and lose one's sight. This kind of disease often forces peasants to give up the fresh and green river valley area - -There spread all over black mosquitoes infected, then move to barrenner area. The doctors use depending on the not rice man (Ivermectin) at present To treat filariasis of a record of end, this kind of medicine can kill son's worm and reproduction ability of reducing the adult. In Senegal and Malian such countries, lose one's sight in a large amount in accordance with the not rice man's treatment and the skin damages patients. But does not depend on the rice man is powerless to the nearly ripe nematode, the latter can cause new infection through the biting of black mosquito exactly. In fact, before this kind of parasite dies finally, the patients all need medicine to control symptom. Meanwhile, scientists have been looking for a and can totally prevent compound infected, for example kill the nearly ripe larva that has just infected. The research group led by the chemist Kim Janda in California Scripps research institute, Santiago of U.S.A. concentrates sight on one kind and is called the chitin On hormone of enzyme, the latter can cast off a skin to solve and restore the crust of the larva time for the last time before filaria's larva of plate tail is ripe. Researchers have sifted and checked 1500 kinds of medicines, aim at looking for a medicine that can inhibit this kind of enzyme. They find the best drug candidate is that a veterinarian uses medicine - -Cyanogen iodine willow amine (Closantel) of chlorine ,This kind of medicine is used for killing the parasite in ox's liver. The research group of Janda fosters nearly ripe a tail filaria's larva in solution with different quantity medicines subsequently. The result reveals, 6 days later, only 1.4% of the cyanogen iodine willow amine of chlorine -treated larva's success of casting off a skin, in contrast to its forming, success rate is 60% that control group casts off a skin. The research group has reported this discovery on the network edition of " institute's publication of national academy of sciences " of U.S.A. of this week. The parasitic disease expert Roger Prichard of Montreal of Canada points out, if chlorine cyanogen iodine willow amine has similar curative effect in the human body, can prevent the occurrence of ones that infected at the beginning then. He say the medicine and depend on the intersection of rice and function of man mechanism at all different, so in the future the latter of any pair demonstrates resisting filaria's population of a tail can treat with cyanogen iodine willow amine of chlorine. Janda shows, he is very optimistic to the behavior of cyanogen iodine willow amine of chlorine, this is because this kind of medicine has already been proved it is safe to the livestock in the farm. He says: "This has accelerated discovery course of the medicine. " But Prichard warns, perhaps the shortcut will not be so fast. He says, a lot of countries including U.S.A. have not sanctioned using cyanogen iodine willow amine of chlorine for all animals. And this kind of medicine will be combined with a kind of protein in the blood together firmly, and this will cause the side effect in the human body. In addition, the research group of Janda must prove, cyanogen iodine willow amine of chlorine can offer the protective action long enough under the intermittent dosage - -In accordance with the intersection of Milan and man the reason why so a successful reason is to only need to take once or twice medicine every year. Prichard says: "The medicine changed from an enzyme with inhibitory activity into a practical application will walk if the medicine changed from an enzyme with inhibitory activity into a practical application there are very long ways. A lot of bottleneck problems need overcoming here. "
Veterinarian's administration may treat the river blind disease