The public must use antibiotic cautiously

The public must use antibiotic cautiously
This newspaper Beijing special despatch ( Reporter to Beijing Wang Le) " super bacterium " --About overwhelming majority it is clinical daily for antibiotic last the NDM-1 intestines bacillus department bacteria of medicine behind reports extensive, cause and pay close attention to continuously both at home and abroad. " the report, on being able to bear the medicine bacterium and have NDM-1 genetic bacterium's relevant problems to explain in detail that the expert understands and able to bear bacterium's knowledge of medicine that Ministry of Public Health releases recently ". It is reported, our country Hong Kong and Taiwan has both already at present found that carry the infeted of bacterium of NDM-1 gene.

The report claims, find the bacterium with NDM- 1 mainly as Escherichia coli at present, pneumonia CrayResearch uncle fungus, sewer intestines bacillus, rub move Morgan fungus, Bowman by bacillus, excrement intestines coccus,etc.. Bacterium these full of the intersection of terms and pathogen, some born in the year of the intersection of human body and normal the intersection of fungus and groups of member, do not usually cause a disease or pathogenic and non- strong; The bacterial infection with NDM-1 gene, mainly take place in the impatient of medical organization, especially the unregulated patient of group of low, normal fungus of organism immunity. It is usually blood, urethra, lung and wound,etc. to infect the position, will not spread in the ordinary crowd of the community extensively.

It is introduced, because the antibacterial medicine is used extensively, it is very severe at present that the whole world is able to bear the medicine situation. All bacteria have already been able to bear medicine phenomena to find, opposing the totally sensitive bacterium of fungus medicine hardly exist. Among them, according to being able to bear the medicine severity, is able to bear golden yellow staphylococcus (MRSA) of west forest of first oxygen , able to bear the mould plain staphylococcus (VRSA) through the ages , able to bear the blue and green mould alkene type intestines bacillus department bacterium of carbon ' Including NDM-1) , suffused with, able to bear medicine move bacillus (PDR-AB) With multiple to able to bear the tubercle bacillus of medicine (XTB) Wait for 8 kinds of bacteria, can be known as " able to bear the medicine bacterium superlying " ; It is able to bear nature not changing pathogenic ability, does not generally produce and infect the type newly either to able to bear the medicine bacterium. But the human immune system only directs against pathogens, can oppose various infection through humoral immunity and cell immunity, the immune system can't overcome bacteria and is able to bear medicines. Bacterium able to bear behind the medicine, treat difficult, treat to the infeted efficient to reduce, case fatality rate increase and hospitalization cost rise by a wide margin.

The expert claims, the mankind mainly expects to overcome bacteria and able to bear medicines through the following ways in and bacterium's struggle: First, research and develop the new antibacterial medicine to being able to bear the medicine bacterium directly. This is the most ideal method, but the result is disappointing, the speed that the bacterium is able to bear medicines and produce far surmounts the antibacterial medicine and studies the speed, and antibacterial the medicine researches and develops the difficulty bigger and bigger. Second, overcome and is able to bear the medicine mechanism, resume sensitiveness that the bacterium opposes the fungus medicine: Such as to bete - inner amide enzyme which the bacterium produced, study synthetic enzyme inhibitor, jointly use enzyme inhibitor and antibacterial medicine. Up until now, there are only bete - inner amide enzyme inhibitor and penicillin (or the very beginning spore's fungus is plain) clinically and suitable for using Compound application, it is still unable to overcome to able to bear the medicine mechanism other numerously. Third, antibacterial medicine substitute products, for instance antibacterial polypeptide, phage,etc., but mostly remain during the course of studying in experiment, it is far away from clinical practice. According to studying in a large amount, the most effective method is to prevent the bacterium from being able to bear medicines, keep the antibacterial medicine activity, the final method to be achieved this purpose is: Use the antibacterial medicine rationally.

To carrying NDM-1 genetic bacterium's question, World Health Organization expresses, the bacterium is able to bear nature and already become the serious global public health problem day by day; And the bacterium of our country is able to bear the medicine question, still relatively severe to a certain extent. Ministry of Public Health reminds the public, are able to bear the medicine bacterium to produce in order to reduce and must use antibiotic cautiously, buy medicine at will, select medicine by oneself, take medicine while being arbitrary non-, park medicines at will. To daily small diseases such as similar cold,etc., don't take the antibacterial medicine easily. Once use antibiotic to treat, should take medicine according to quantity on time, maintain the valid density in the body of medicine. Ministry of Public Health reminds at the same time, the public should pay attention to the personal hygiene, take exercises, improve resistance, and prevent infective disease and some infectious diseases through vaccine inoculation.


The public must use antibiotic cautiously