The immunity is studied and claimed: Have in the human body " The natural killer " Can " hunt cancer "
The source of 15:47 on February 06 of 2009: The youth consults Author: Li Yue
The intersection of American and one new discovery of scientist, let we to human the intersection of immune system and " how rows of soldier structure the formation " There are new knowledges. Considered to be in the past " Brave but not resourceful " "natural killer " Cells (natural killer, are abbreviated as NK cells, call " natural killer " too Cells) ,Have been in fact underestimated. If develop their latent energy carefully, the devils of AIDS and cancer may fold one's hands for capture. The intersection of first line of defence and these latest research of human body publish at British Nature published on January 11. The little biologists of the person in charge of this research, University of California Louises? Lanier says, human immunoreaction is usually divided into two kinds - -Congenital immunity and adaptive immunity. People have a congenital immunological function when born in, mainly by some " protective screens " For instance skin and mucus, and some immune cell such as NK cell,etc. form. NK cells were probably found, it was a kind of big granulous lymphocyte in 1970. It is known as " The natural killer " ,Because they are not like toxin cell T cell, distinguish and react to just confirm the goal is " hit out " through the antigen of the immune system . NK cells can be hit out voluntarily, kill the tumours or bad cells infected by the virus. At the international amynologic forum that Hawaii of U.S.A. held in 1986, this kind did not need to distinguish and attack " invadors " through the antigen Cell,last " it is natural killer " (NK) " Cells. The adaptive immunity different from congenital immunity, is mainly implemented by T cells and B cell and other immune cells. They want, cost time could cultivate, confront with each other antibody to invade the virus several week probably. NK cells are human " The loyal and brave bodyguard " ,It is the first line of defence of the human body, infects it while happening for the first time, NK cells will take the lead in " check and kill " . T cell and B cell can pathogen study experience invade, from last time, raise defence capability, in order to should invade to twice of the pathogen ready. There are T cells and B cells " The memory function " ,Immune memory can be kept for a long time, can destroy for several years and even count the same invador ten years later. Various virus vaccine which we used, it is the memory function of utilizing adaptive immunity cells, but the scientists do not think before this NK cells have a similar memory function, therefore it is difficult to " play the leading role " in virus vaccine is researched and developed . The little biologists whose NK cell actually have University of California of memory Laniers say: "We thought in the past NK cells were blind while killing invadors, deal with the immunoreaction that is infected each time to look at like for the first time, the life-span of NK cells is very short after all, only two or three weeks. But the test result makes us greatly surprised. " Research group of Lanier inject one huge to take virus (the very much common on mankind virus cell on mouse, can cause chicken-pox and venereal disease,etc.) ,Hereafter, the NK cells in mouse's body react at once, its surface produced a large number of receptors and locked and checked that killed the cells infected by the virus. Several weeks later, researchers find, some NK cells producing the receptor to virus are hidden in the lymphoid tissue. Researcher draw, come out some NK cell these, inject, get, infect cell to be huge to take 2nd batch of the virus, test on mice, T cell and B cell of these mice,etc. have already been destroyed. As a result, during less than one week, produced the NK cells killing huge virus characteristic of melting of cell in the body of the second batch of mice specially in a large amount, the quantity is surprising, this kind of cell in the spleen and liver, including 100 times even 1000 times of the normal situation. Lanier says: "We find through the experiment, NK cells have certain immune memory to the pathogen, can offer more high-efficient immune measure pointedly. " Lanier says, the new discovery contributes to the research and development of vaccine. "Since NK cells have a memory function, can bring into play the function of NK cells in research and development of vaccine. Its still perhaps study on vaccine of HIV plays a role in inspiring. Previous finding, some people, to HIV (HIV) Stronger resistance, infect, go through a longer time will have illness coming on. Does this relate to NK cell? The understanding NK cells that it can be better, we can find the method to control HIV. " The model of immunologist of medical college of Harvard University? Arnd Rui'an thinks: "The explanation of NK cells may be wrong on the current textbook, the increasingly many discovery lets us find out about NK cells, the cognition of the human immune system has entered one step too. " The model? Arnd Rui'an had published the article to point out on Nature, the experiment revealed in 2006, the life-span of some NK cells has several months long. Expected to give full play to one's remarkable skill to that AIDS study expectation at anticancer, today, the research of NK cells has already reflected in anticancer research. It is reported, usually the human body will produce thousands of cancer cells every day, our immune system controls for 24 hours through the blood circulation. NK cells have extremely strong checking that kills function on cancer cell, once find the cancer cell, know instead of combining, will destroy the cancer cell and kill it in 5 minutes at once, it is high-efficient " Hunt the cancer expert " . In recent years, the scientist utilizes the characteristic of NK cells, research and develop medicine and method of face-off cancer. The physician of Japan once trained the cancer patient's NK cells outside the body, after reaching certain amounts of, and then pour into patient's body. Particularly, collect the intravenous blood of patient of 20- 30 ml at first, isolate the NK cells of small quantity very much from it, it is stimulated and activated with various growth factors and then. After cultivation of two weeks, the small quantity very much of these scripts and the quantity of NK cell not strong of the activity rise to 10- 60 hundred million, and then pour into patient's body by means of bit through the vein. Generally speaking, nearly there are 1- 5 hundred million NK cells in a healthy human body, pour into internal NK cells, have strengthened the killing capacity to the cancer cell greatly. NK treatment totally adopts patient's own cells, so without agony, there are no side effect and rejection, it is a directly effective anticancer method, but the cost is very high at present. As technology being further ripe, the cost is reduced greatly, can well come into common people's home to deal with the evil spirit of cancer. Activity insufficient vigor and quantity that will cause disease NK cells of NK cell are the important insurance of the health. American center for disease control (CDC) The report last year revealed, the production of nearly all diseases related to the fact that the activity of NK cells is not obviously enough. Lanier, little biologist of University of California, says, " when people suffer from disease, no matter chronic, sporadic or acute, the activity of NK cells is under average level. Let NK cells be returned to the high-level activity, it is the best therapeutic disease method. " In fact, the reducing of the activity of NK cell is that some kinds of pressures cause. When the body can't fully adapt to the environment, the following one is that the body function drops. Do not have enough sleep, overwork, the emotion is unfortunate, lacks sport, athrepsia, is exposed to the toxin of germ etc., will all cause the pressure to the health. According to the introduction of Lanier: "At the excessive pressure, the human body will produce the harmful change, especially immune system. Study to reveal, there are certain interdynamic relations between activity and emotional pressure of NK cells. Can't deal with the out of control of person and behavior in the pressure, there is a question of NK cells with insufficient activity. " Even if is a provisional pressure, will lead to the fact it is reduced that the activity of NK cell is acute, but adjust and have a rest appropriately, the activity of NK cell will be promoted. For example, when being too tired and malnutritive, so long as have a good rest for a few days, eating the appropriate food can resume. However, when our lasting place is under the environment of life harmonious in pressure, the immune system is being weakened constantly, may cause the emergence of cancer or other chronic disease.
The immunity is studied and claimed: Have in the human body " The natural killer " Can " hunt cancer "
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