Immunology is studied: Biomedicine and growing point new in industrialization

Immunology is studied: Biomedicine and growing point new in industrialization
"With the crossing of other medical science and discipline research field of the life, have promoted the development of immunology and other disciplines greatly, will contribute to knowing in the amynologic respect of foundation thoroughly to amynologic theory of the classics, this kind crossed to drive the development of other medical science and life discipline too. "

Cao XueTao

Academician of Chinese Academy of Engineering, medical immunology national key laboratory / amynologic professor of research institute of the second army medical university

Clinical value is more obvious

In the past 10 years, amynologic development has changed with each passing day, the new break-through has appeared in the amynologic theoretical research of the foundation, new amynologic technology is emerging constantly; Meanwhile, the crossing more extensively and deepening of immunology and other life sciences and medical discipline, these, for help people through amynologic visual angle and method, strengthen, take place to disease understanding and prevention and cure of disease of development mechanism play a positive role, also promoting amynologic theory and technology to have illness coming on at great clinical disease, the mechanism study and prevent the application being treated.

The immune basic concept is that an organism is discerned " Oneself " Until " it is not I (dissident) " , the immunity produces, reply so as to drive out " The dissident " Antigen, or induce the immunity to tolerate in order to keep one's own internal environment steady. Immunology is discipline of studying structure of immune system and function, involve the immunity to discern, immunity reply with immunity tolerating / a great deal of the intersection of immunology and basic the intersection of science and law and the intersection of mechanism and research and immune mechanism of immune adjustment,etc. play a developing role at relevant disease, application in amynologic technology is in the disease diagnosis, treat and prevent from,etc..

Clinical and amynologic clinical value is more obvious. Immunology has already almost permeated every corner through the clinical one, has employed amynologic technology and method to study and treat disease and is being paid attention to. At present, the focus of studying in clinical immunology includes the achievement that studies in application foundation immunology, expound tumour, infect, transplant the morbidity mechanism's research, specificity of repelling, one's own immune disease,etc. important disease and prevent and treat the setting-up of the measure, reseach of new vaccine, and with developing relevant biologicals of immunity,etc..

Basic immunology combines closer with clinical immunology, basic immunology offers the theoretical direction for development mechanism and therapeutic studying of numerous immune relevance diseases, the intersection of HIV and vaccine develop, to drug therapy,etc. target of rheumatoid arthritis. Meanwhile, the clinical and amynologic practical problem offered the new demand for development with amynologic foundation too. Development, setting-up of the experimental animal's model, study the human disease problem in purpose as Tetramer-peptide measures CTL technology.

The crossing of immunology and other medical science and discipline research field of the life, have promoted the development of immunology and other disciplines greatly: If immunology and bioinformatics, structure biological crossing, study immunity discerning, immunoreactive emergence mechanism at the molecule atom level, will contribute to knowing in the amynologic respect of foundation thoroughly to amynologic theory of the classics, this kind crossed to drive the development of other medical science and life discipline too.

Still have disparity with the developed country

I want to use " The capable and laboring, existing light spot that ago, and then flies overing " To express it to amynologic research history, current situation and future elementary understanding of our country.

Since middle and later periods of 1990s, immunologists of our country have issued the amynologic research work of finishing on the international amynologic magazine at home progressively, thesis quantity and quality are promoting constantly, the research contents nearly involve foundation and each field and front focus of clinical immunology. Study the technological platform to already set up in immunology of our country at present, has studied the team and already basically taken shape, it is progressively clear to study the direction, the goal in research is further condensed, so, are convinced and studied and realized the great-leap-forward development in the next 10 years or 20 years in immunology of our country, reach the world level in some fields.

Here at the time of the promising and confidence, we should realize soberly, compare with importance in life sciences with amynologic discipline in the whole medical science, immunology of our country is studied in the national system of scientific and technical innovation, even the position in medical science and life sciences domain is still not prominent enough, study the level and still have greater disparity and deficiency with developed country immunology.

For example, though our research contents are more extensive, there are few many peaks of mountain, light spots are not many, lack still receive international immunology that counterpart approve, study the unique technology system probably, breakthrough academic view or academic thought of original immunology, still lack the accumulation of the characteristic systematic theory and can assault the challenge work of the traditional amynologic view, have not almost opened the new research direction or new research field that can let the international counterpart follow the trail of, also the one that almost have no scholar of our country to find at first made the international counterpart follow " The immune member of the star " Or " star's immune cells " ; First-class immunologist not still receiving the international counterpart's generally acknowledged leading type in the international amynologic field, there is not any research work of finishing in the native country of the mainland that can be written into the amynologic textbook of authoritativeness that world approved.

In addition invite, it acts as Symposium to be few in of our country scholar that level make a speech the intersection of IUIS and conference, it takes on foreign immunologies to be few even in relevant the intersection of magazine and of our country scholar of editorial member; Still lack the ripe model of experimental animal especially disease animal model of the uniqueness, condition gene reject little mouse model prepare system to be yet complete even; With the high-tech enterprises of living beings and combine clinically it is not close enough either, these development not enough to limit immunology of our country to study. We should overcome and remedy these weak points with the positive psychology, it develops amynologic research and course of development of our country to overcome and remedy these insufficient course.

It is the biological industrialization that creates the new growing point

With merging alternately with the setting-up of the new technology system of the biomedical research, immunology faces a great deal of opportunities for development as a front discipline, some technological difficulties that perplexed the immunologist in the past are broken through to some extent with setting-up of the technological platform of some high flux, immune phenomenon difficult to measure or the changes of immune cells and the molecule of the past, easy to measure with setting-up and application of the high specific technological method of the high sensitivity.

As system being medical and transforming the constant promotion of the medical idea, the unprecedented situation has appeared in amynologic basic research and clinical practice, rounding the important science problem of diagnosing in early days, preventing in early days and treating in early days etc. from great disease in the clinical practice, launch innovatively and study more and more by the immune educational circles and pay attention to. Immunology and preclinical medicine and clinical medicine further launch the work of merging alternately around front and difficult point of transforming medical science, still at the starting stage at present, believe that will solve and perplex human great disease and play a strong role to help in the future. Believe a immunologist once in how the immune system discern the invasion of the external pathogen and start naturally and the acquired character immunity is replied, and discern and break through to some extent on one's own basic science question of immunology in order to keep one's own immunity tolerating,etc., bring the new hope for infection, tumour, the intersection of organ transplant and the intersection of repel, one's own immune disease and irritated disease,etc. and human great diagnosis and prevention and cure of disease, will create the new growing point for the development of high-tech industrialization of living beings.

(staff reporter Pan Feng is " accelerating the Chinese medical mode to change according to the author, promote the scientific question of the system reform of China's medical and health " Report at the S13 scientific meeting in Fragrant Hills once put in order)

Immunology is studied: Biomedicine and growing point new in industrialization