Immune cells are variable " The neuronal killer "

Immune cells are variable " The neuronal killer " Increase the ill danger of Parkinson's disease
Reporter Li XueMei

Paris, January 19 (Xinhua) French researchers found a few days ago, behind a kind of immune cell invaded the person's brain, will change" The neuronal killer " ,Thus has increased the danger that people suffer from Parkinson's disease. This result of study will be offered the new thinking in order to develop specific drug curing Parkinson's disease.

French Curie researcher Ai DiAn of the university? Hill He Stevan and Na Shi? Say on the latest American " clinical examination magazine ", they dissect the corpses of some persons who died of illness suffering from Parkinson's disease before death in the promise, the result has found a considerable amount of T-CD4 lymphocytes in the dead's brain. This kind of lymphocyte is a kind of immune cell, possess and discern pathogen such as virus, bacterium and command other immune cells to attack the function of the pathogen, generally speaking will not appear in people's brain. Researchers think, once this kind of lymphocyte invades people's brain, will kill neuronal cells, make people suffer from Parkinson's disease.

Researcher's experiment that the use mouse has carried on subsequently, the result has verified their supposition. Once this kind of lymphocyte disappears in the mouse brain of Parkinson's disease from suffering from, symptom of the disease mouse will get obvious improvement. In addition, researchers have also found a kind of existence which is called FasL molecule in disease mouse's brain, it is utilized that T-CD4 lymphocytes are exactly it to lure neuronal cells into " Commit suicide " .

Researchers think, if can try to prevent T-CD4 lymphocytes from invading people's brain, can reduce people and suffer from the risk of Parkinson's disease.



Immune cells are variable " The neuronal killer " Increase the ill danger of Parkinson's disease