China's disease accuses of revealing at the news briefing that the centre and office of security council of food of Nanjing jointly held yesterday, the pathogenic case of little suspected lobster presented in Nanjing belongs to Haff (Haff) Disease.
Then what disease does Haff's disease plant on earth? According to the introduction of nutrition and food security researcher Wu YongNing of Center for Disease Prevention and Control of China, in autumn of summer of 1924, presented the prevalence of the acute poisoning muscle disease on Haff seashore of the Baltic Sea, it is shown as that the serious stiff pain of muscle appeared suddenly, there are not abnormal state, generated heat and liver splenomegaly of central nervous system, some patients have coffee-like urine, there are very great differences in clinical manifestation. Most patients return to normal rapidly, death of the serious one that only specific, the same season and the same area in 9 years hereafter have found about 1000 patients, and find these patients relate to drinking water products.
What disease is Haff's disease on earth?
Summer and autumn high hair, little lobster, eel, cod,etc. can all cause a disease
Yesterday, specially introduced Haff's disease on the websites of department of public health of Jiangsu Province. Say, in 1924, reported the striated muscle of the unidentified reason caused by edible aquatic products dissolved the case of syndrome abroad for the first time in the world on websites, because happen in Haff area along the Baltic Sea, call that Haff's disease (HaffDisease) ,This disease suspects that relates to a kind of toxin not confirmed yet. Unexpected outbreak that the typical clinical manifestation of Haff's disease is the striated muscle dissolved, follow muscle touching a tender spot, stiff, soy sauce urine,etc..
And just on August 29 this year, the scientific squirrel knows to members, the biological master and visits and knows You to publish the article in the media <
Between August and March of 1997, the seriously uncomfortable case of aching etc. muscles happened after eating big mouthfuls of blusher fish in U.S.A.. After the epidemic situation appears, U.S.A. eats the medicine office (FDA) ,Local hygiene, environmental department have participated in making investigations, finally " evil backstage manipulator behind the scenes " of the epidemic situation Target it as Haff's disease.
Haff's disease is a kind of disease with very heavy doubts and suspicions. It is the high-incidence season of Haff's diseases in summer and autumn, fresh water cod, eel, pike, little lobster,etc. have pathogenic records, the onset area includes Sweden, Soviet Union, U.S.A., Brazil and Germany. Will it be will it be the first ten days August 2000, appear, eat the intersection of La and the intersection of Haff and the intersection of disease and patient that Ku cause in succession in Beijing area. Haff's disease causes the cause of disease to be plain and unidentified so far specifically, only knows and takes in the aquatic products to have something to do with.
"From present's view Haff's disease is all that edible aquatic products cause. The report according to foreign countries is serious will cause the renal function to be depleted, no depleted renal function has not happened yet to the patient accepting for medical treatment in our hospital, it is mainly the aching of muscles, the muscles of the back ache many. " Chief physician of the People's Hospital of Jiangsu Province Xing Chang wins to point out, comparatively the condition is a little lighter than foreign countries report in the case which this institute finds at present.
What on earth is the cause of disease of Haff's disease?
Not so obvious at present, the suspect may be " toxin of sea anemone "
Since Haff's disease breaks out for the first time in 1924, various countries have done the discussion to the reason of this disease, have not found the precise cause of disease. Then, which had investigator of U.S.A. done 6 cases to investigate at that time?
Swim and know You to point out in the article, the medical history reveals patient's edible aquatic products within 24 hours before having illness coming on. Two people vomit after having a meal, symptom of persons who vomit is relatively light, it is relatively low too that biochemistry tests the index, so the cause of disease eats the source possibility of the toxin relatively great. Meanwhile, the investigator analyzed the patient's food too. Source, how washing, investigation how to cook are in process too. Found finally, big mouthfuls of blusher fish's some that these 6 people took came from the supermarket, some came from the market, but the capital is cooked through the high temperature. The toxin of fish's corruption and production has been got rid of.
Subsequently, the environmental supervisor begins to pursue the source of the food, investigate that catches large place and quantity of mouthfuls of blusher fish. They catch other fish's samples in the water areas to measure these fish, have got rid of most known toxin.
Finally, researchers carried on the toxicology test of the unidentified composition. Raw fish and well done fish draw with three kinds of different solvents respectively, then throw something and feed extracts to the mouse, and inject in its abdominal cavity. As a result, a kind of extract of the well done fish makes the mouse damage with similar symptoms such as the urine of soy sauce,etc. muscles. Researchers drew the conclusion at last, that caused Haff's disease was a kind of unknown toxin that can be soluble in the non- polar fat, this toxin is still stable under the high temperature, the cooking is unable to enable its elimination. At present, researchers think primary " suspect " It is the toxin of sea anemone (palytoxin) in ocean fishes' body And the similar toxin in fresh-water fishes' body.
Through this investigation, scientific research personnel have a more deeply knowledge of Haff's disease. 2001, Louisiana state of U.S.A. has an area of the area in 30 miles, the epidemic situation of rhabdomyolysis takes place in 3 to 16 hours after 9 happens to get up to eat the little lobster in 7 days. The doctor judges for Haff's disease and for the treatment to the ill rapidly according to the previous result of study rapidly.
Pay close attention to rhabdomyolysis
Can cause too after moving vigorously " The skin is dissolved "
The reporter interviews to learn, Nanjing will accept the patient whose muscle dissolved disease of horizontal line for medical treatment every year, but the morbidity is not high, but mostly rely mainly on distributing. The yellow justice dragon of Deputy Bureau Director of Municipal Health Bureau of Nanjing has shown, the morbidity is not high at ordinary times because of rhabdomyolysis, have not listed in and monitored the category, so not easy to judge whether the patient of this year rose by a wide margin than in the past. But clinicians in Nanjing generally reflect, the patient of rhabdomyolysis is very centralized this year, and a lot of are whole family.
The manual labor of moving, strong vigorously, or traumatism is pushed, take the hypotensor, asthma medicine or spirit medicine for a long time, also may cause rhabdomyolysis. In 2002, two new recruits suffered from rhabdomyolysis after shouldering a heavy task cross-country running of 5 kilometers. Likewise, still accepts some for medical treatment and does not love sports at ordinary times on clinic, assault the small white collar of fitness on festivals or holidays. One guy and people bet, force, do more thanth push-up continuously once, the movement is excessive, the result gives " dissolve " of muscles (used after a verb to indicate the completion of an action).
Likewise, on " lobster's door " Before this, it is wounded and weighing the important cause of disease that was once rhabdomyolysis too wounded to crowd. Point out expert, the any due to reason one body,especially whether limb is pigeonhole? cottonrose hibiscus Suan of duckweed of silly Jia Lu Yu of ; Pay and take on the dark green 's squid of brown school of the sixth of the twelve Earthly Branches of Na of Xuan 's mirror and stop Yu duckweed cottonrose hibiscus Buddhist nunnery in good fortune of the gown ? One and Yu DanDan)
" Haff's disease " Its mystery has not been analysed and explained for more than 80 years Cause a disease after the edible aquatic products
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