" China's symbol " First stage clinical trial of vaccine of AIDS is safe and effective
AIDS, Center for Disease Prevention and Control of China, prevent control centre chief expert a ring Shao say in Beijing on the 1st, a kind of AIDS with independent intellectual property right in China and a clinical trial of vaccine has already been over at first stage, the result reveals vaccine " very safe, the result is very good " .
The situation that China prevents and cures AIDS at present is still very severe, the public pays close attention to the reseach progress of vaccine of AIDS very much.
Compounding vaccine of AIDS of vaccine of DNA- the Temple of Heaven jointly developed by the institute of biological products of Center for Disease Prevention and Control of China and Beijing begins to enter since December 1, 2007 Clinical trial of period of walking. At present, clinical trial is first stage (namely a stage) Already been over, has begun to enter clinical trial for second stage (namely b stage) .
A ring of of developing the person in charge of the group as vaccine Shao was sponsored in the centre of development of China's biotechnology " The healthy scientific and technological summit forum on the fourth " Have had and also revealed the details of the vaccine clinical trial. He says: "By the look of first stage, our vaccine is obviously better than vaccine in the world, result of having three injection more than foreign countries in result of having one injection. "
The animal experiment before being earlier shows, this vaccine getting inducible very good body fluid and cell immunoreaction in little mouse and monkey's body, and can infect the people / monkey's immunity defective virus to monkey's body and have protective action.
Mentioning this " China's symbol " AIDS, at the prospect of vaccine, a ring Shao keep very prudent attitude. He says: "We can't be unrealistically optimistic yet, whether these results can go to the clinical stage, one, still remain to verify. "
Before the this according to one ring introduction Shao, the intersection of AIDS and immunity of vaccine this select from the intersection of China and prevailing most wide the intersection of HIV and malicious of CRF-07 originally, including gag, pol, env and four genes of nef. The carriers of vaccine select virus of a of vaccine of the Temple of Heaven for use, because virus of this vaccine has been applied to variolosus vaccine of China extensively, security has already got the abundant verification that several hundred million crowds employed.
On December 1, 2007, vaccine has already passed the strict qualification concerned, quality is qualified, obtain national food medicines and supervise the administration bureau sanctioning carrying on a clinical trial. If test clinically successfully at the ongoing vaccine b stage at present, scientific research personnel will also carry on the long-term research at stage and one.
The research in the field of vaccine of AIDS of international community has had more than 20 years so far. Consumed a huge sum of moneying carries on more than 100 vaccine clinical trials, there is no effective vaccine to come out yet at present, two clinical trials that has already finished one end in failure. Announce the AIDS vaccine failing is protein vaccine or non- duplicating carrier vaccine in the world, vaccine dies.
Differ widely with popular AIDS vaccine design idea and technological route in the world, it is the duplicating virus carriers of vaccine that China is carrying on clinical trial, it is vaccine vivid.
This vaccine has researched and developed and obtained national 863 Program subject and subsidy about project of European Union.
" China's symbol " First stage clinical trial of vaccine of AIDS is safe and effective
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