BJ Union Hospital finds hepatocarcinoma examines the new method early

BJ Union Hospital finds hepatocarcinoma examines the new method early
It is reported ' Reporter Wang XueFei) Mao Ray of liver surgery of BJ Union Hospital wait and issue a result of study on " China's medical magazine " recently: Through measuring the serum mark thing - -Glycoprotein of golgiosome - 73( GP73) Come, carry on hepatocarcinoma diagnose sensitiveness its can up to 76.9%, far higher than traditional the intersection of method and first the intersection of child and albumen (AFP) in early days Determination. This is the only report about GP73 coming from Asia area up until now.

According to counting recently, increase two cases of hepatocarcinoma newly and happen in the world in China in the same way each time. It saves key of life, patients of hepatocarcinoma, to be to examine, manage early early, commonly used early inspection method have images learn, find with the serum mark thing in being clinical. But the image learns to check hepatocarcinoma that can be found and often already gets 0.5 centimetres of diameter - more than 1 centimetre long. The most frequently used hepatocarcinoma is sifted, checked in early days the serum mark thing is first child albumen on clinic, but it is only 56% that its sensitiveness is average. It is possible that it is offered for finding out the new hepatocarcinoma mark thing that the albumen group rising in recent years learnt technology.

Researchers such as a thunder of mao,etc., to 37 hepatocarcinoma patients, person who carries virus of 25 hepatitis B, AFP, GP73 and relevant hepatocarcinoma serum index of 12 persons who didn't get hepatopathy and 99 normal healthy volunteers have been measured and compared. Found finally, all can detect GP73 in serum which examined people, but the levels were very low among healthy crowd and person who didn't get hepatopathy. Although GP73 level of the person who carries virus of hepatitis B is higher than the health and person who didn't get hepatopathy, but is well below a hepatocarcinoma patient. GP73 level in the hepatocarcinoma patient is the highest, it is 20 times that of person who carries virus of hepatitis B. GP73 sensitiveness in the hepatocarcinoma patient is up to 76.9%, the specificity is up to 92.8%. And the sensitiveness of AFP is only 48.6%. Study, brief on still, GP73 still keep certain level in postoperative week such as patient such as hepatocarcinoma, obviously dropped in until 1.5 years after the operation 2, there is one that degrades course in the blood to brief on GP73 albumen. In the intersection of hepatocarcinoma and patient, the intersection of GP73 and high or low prices and tumour size, have obvious relevance in grades.



BJ Union Hospital finds hepatocarcinoma examines the new method early