Prostate cancer examines the specificity and rises to 50 early

Prostate cancer examines the specificity and rises to 50 early
It is reported ' Reporter's grandson Ni HongZhen, root reporter of country) Through research and exploration of the past ten years, Fudan University subsidiary tumour hospital leaf makes the seminar that big Professor head the list of signers, to of our country public the intersection of prostate and the intersection of cancer and characteristic of having illness coming on, initiate many tumour mark the intersection of prostate and cancer of jointly detecting etc., diagnose system in early days in the urine, take the lead in setting up compatriot's prostate cancer curative effect and surviving to predict models. Its research results have already been popularized and applied in over 8500 patients of domestic over 60 hospitals, have improved prostate cancer early diagnosis, complex treatment level of our country notably, and improve the patient's existence, quality lives. This achievement obtains the first prize of the progress prize in science and technology of Shanghai recently.

Diagnosed prostate cancer in the past, generally adopt the prostate -specific antigen to check (PSA) ,But it diagnoses accuracy is not high. For solve difficult problem this, leaf make the big seminar get PCA3, TMPRSS2 in the a of urine out of for the first time: New mark thing that ERG, annexinA3 and methyl amimoacetic acid,etc. diagnosed as prostate cancer, should also puncture and examine technology alive with three-dimension stereoscopic localization of formation of image and individual of magnetic resonance spectrum, further improve the prostate and diagnose the system in early period, make the sensitiveness that prostate cancer diagnoses in early days improve from 80% to 95%, specificity improve to 50% from 25%, remedy deficiency that PSA check, make prostate cancer the diagnosing rate is raised from 19.8% to 40.7% in early days, and optimized the prostate and punctured and examined technology alive and made the infection rate drop from 9.8% to 4.1%.

Leaf make the big seminar initiate prostate cancer part infringing, shifts, curative effect and survives and predict model and new indexing even, at setting up domestic first more than the intersection of centre and the intersection of prostate and the intersection of cancer and foundation of database, announce the intersection of Chinese and the intersection of prostate and overall prognostic state, patient of cancer, for the first time, prove, establish, suit the intersection of compatriot and the intersection of prostate and cancer, make membrane, infringe with the lymph node shifting, predicting models for the first time, establish and popularize and apply PSA and is reduced by half the time law, the situation that the cancer patient of prostate always survives that predict later period, have offered the categorised basis for optimizing the comprehensive healing solution.

It is reported, androgen is not that the reliance causes cancer patient's main causes of death of prostate. Leaf cancer complex treatment norm of prostate and tactics of making the optimization that the big seminar popularizes to the whole country and setting up later period, survival rate is improved from 33% to 41% in 3 making androgen not rely on cancer patient of prostate, make patient urinate, obstruct IPSS grade, drop from 29.7 points to 9.7, life the intersection of quality and KPS grade, raise to 77 from 55, have improved the patient's life quality notably.



Prostate cancer examines the specificity and rises to 50 early