The medical application of regeneration makes the new achievement

The medical application of regeneration makes the new achievement
It is reported ' Reporter Ge Jin) The multi-functional stem cell exists in the initial embryo of the vertebrate, it is one kind that is divided into the not cells of the division of all body cell ability. When this kind of cell splits up, begin to form three germinal layers most, is known as other germinal layer, middle germinal layer and inner germinal layer respectively. Among them the other germinal layer will be divided into nervous system and skin epidermis. It was to control the multi-functional stem cell's hereditary gene of development of germinal layer outward that Japan cut the research group of the chemical research institute and discovered, Japan paid attention to the chemical websites of research institute to report this news recently.
In the past, people have already found, the germinal layer (development becomes muscle, skeleton, blood,etc.) in the multi-functional stem cell's development of splitting up becomes With the inner germinal layer ' Development becomes digestive organs, respiratory apparatus,etc.) Known as " Nodal " by one kind Secretion protein control. What it is and really material determine multi-functional stem cell development of germinal layer understand never outward.

The scientist of Japan who pays attention to the chemical regenerated science comprehensive rearch centre of research institute tests many times through 20,000, take and inject the micro- gene into frog's embryo method of the African money, has verified finally one is known as " XFDL156 " Core proteins inner to be multi-functional without being determined stem cell genes hereditary where germinal layer split up outward. In addition, researchers also carry on the test with white mouse's embryo, in the really mammalian embryo of card is equivalent to " XFDL156 " Liang plant known as"Zfp12 " With " Zfp74 " Have by function that is the same too gene. " XFDL156" Bind in the nucleus with well known anticancer genetic p53, and p53 is besides inhibiting the cancer cell from growing, growth of germinal layer still can promote, test prove " XFDL156 " The division of germinal layer, promote the growth of the other germinal layer while inhibiting by hindering the activity of p53.

In production and reseach of the multi-functional stem cell, mainly have two kinds of routes of embryo's stem cell and ips cell at present, want, develop regenerated clinical practice of medical science into it, accumulate through a lot of tests. Control principle that the germinal layer splits up that this people clarify the multi-functional stem cell in the molecule rank outward for the first time, researchers think it is an important achievement that this research results can be called in application of regenerated medical science.



The medical application of regeneration makes the new achievement