Regenerated mouse's retinal cells succeed

Regenerated mouse's retinal cells succeed
Thesis author: MikeO.Karl periodical: PNAS

The regenerated one has not dashed for ward cells long, among them red is the nucleus, the others make up for being green. According to medias of foreign countries, success for the first time of the scientist of University of Washington lets the regeneration of mouse alive get off retinal cells, this has offered hope that succeeds for human regeneration eyes cell, thus can be expected to resume some blind persons' eyesight. This research results issued U.S.A. " institute's publication of national academy of sciences " that publish on November 24 Have.

The retina lies behind eyes, its function is to transmit the light in the brain through the neural pulse. Previous research work shows the retinal nerve cell (M Ller cells) Can foster out in training wares. Tom and Lee He of University of Washington says: "This kind of cell exists in all retina of all vertebrates, so the regenerated source of cell appears in the human retina. " The scientist will further study the treatment and damage the method which causes blindness because of the retina. What express birds warm-blooded animal like mammal, they limited in retinal ability of cell in regeneration Li, and the fish are cold-blooded animals, can regenerate the retinal cells of all kind.

Make the retinal cells of mouse's regeneration considered to be mankind's biological ideal mode, but it is difficult to accomplish this. Researchers inject the material into the retina, in order to remove ganglion cells (a kind of nerve cell existing near the retinal surface) With dashing for ward cells long. Later injected the medicines of fiber original cell growth factor, epidermis growth factor and insulin,etc. into eyes, can stimulate the retinal nerve cell to resume splitting and hyperplasia, some has been turned into a ripe nerve cell, including dashing for ward cells long. What say have long to dash for ward cell, can regulate the intersection of sensitization and electric signal of device, find out sport and look at to eyes very important night Li.

However, researchers find a lot of have been died within the first week when form by retinal neural cell division and outgrowth original cell, but try to convert these cells which dashed for ward cells to having long and survive for 30 days at least. The scientist does not know to this phenomenon what it is about. Lee He says: "Though we have not got a large number of new nerve cells, we can get new dashing for ward cells long. "

The scientist says, the retina of the skin is like CPU of the computer, one layer of retina looks like the main board inside, if change new CPU for the main board of a piece of necrosis, no matter how this CPU quality is high, it will be unhelpful. And the retinal cells of regeneration can well solve this problem. (Source: Yeah visits Sonett)

Regenerated mouse's retinal cells succeed